About OpenEvidence (Openevidence Inc.)
OpenEvidence is trusted by hundreds of thousands of verified healthcare professionals to support high-stakes clinical decisions at the point of care with answers that are sourced, cited, and grounded in peer-reviewed medical literature.
Now sourcing from over 300+ medical journals, as well as the FDA and CDC. OpenEvidence is an official AI partner of The New England Journal of Medicine and the Journal of American Medical Association (and their 11 specialty journals), and has content agreements, partnerships and collaborations with:
NCCN
ACC
ADA
ACEP
AAFP
AAOS
AAOHNS and more.
OpenEvidence is only available for health care professionals. Users must verify their health care professional status before using OpenEvidence.
TESTIMONIALS
“I've been using OpenEvidence for the last week - it has been amazing! Able to narrow down on results quickly and find information that I wasn't able to do with Google/PubMed searches on my own.” - Dr. John Lee, MD. Physician & Faculty Member, Harvard Medical School
“OpenEvidence can be the foundational technology to power all clinical decision tools.” - Dr. Antonio Jorge Forte, MD. Director of MayoExpert, Mayo Clinic
“OpenEvidence is more up-to-date than UpToDate. And more useful regardless, since it’s interactive, and you can ask it questions, and get very specific answers about specific medical fact patterns in a patient case. It’s like having a curbside consult with a team of expert physicians, but that you can carry around with you in your pocket.” - Dr. Ram Dandillaya, MD. Clinical Chief, Department of Cardiology, Cedars-Sinai Medical Center
“I am in community practice and medical director of a community cancer center. OpenEvidence has been an incredible lifeline for daily practitioners.” - C.J., Oncologist
“OpenEvidence is absolutely fantastic. I use it a gazillion times a day.” - J.A., Neurologist
“OpenEvidence’s efforts to make medicine more evidence-based are invaluable. The shift from judgment to calculation can reduce the level of noise currently found in medicine.” - Daniel Kahneman, Nobel Prize Laureate (In Memoriam)
“It is light years ahead of the next best medical oriented AI I have used.” - R.E.., Oncologist
What's New in OpenEvidence (v2.9.9)
* Streamlined experience during answer writing
* Performance enhancements
OpenEvidence Contact Information
To reach OpenEvidence customer service and technical support, use the official channels below. For the fastest reply, choose the developer's official website.
OpenEvidence Subscription, App Deletion & iOS Support
How do I cancel the OpenEvidence subscription?
Open Settings on your iPhone or iPad, tap your Apple ID (your name) at the top, go to Subscriptions, select OpenEvidence from the list and tap Cancel Subscription. Cancellation takes effect at the end of the current billing period; you can keep using the app until then. See Apple's official subscription management page for details.
How do I delete the OpenEvidence app?
Touch and hold the OpenEvidence icon on the Home Screen, choose Remove App and then Delete App. Important: if you have an active subscription, deleting the app does not cancel it automatically - you must first cancel your subscription using the steps above.
OpenEvidence purchases, refunds and billing issues
Report billing or refund requests for OpenEvidence through Apple's Report a Problem (reportaproblem.apple.com). For the app's own technical support and contact, use the developer's official website or the OpenEvidence App Store page.
Distribution of OpenEvidence Reviews
Of the last 59 reviews shown, 92% are positive (4–5★) and 8% negative (1–3★). App Store overall rating: 4.9 / 5
OpenEvidence Positive Reviews and Ratings
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The team has built something awesome!! If you’re someone who’s trying to look up the right thing to do and already trying to chatGPT cardiac questions- this is the best AI tool (ignore ChatGPT!!). It’s well resourced with high impact journals. It’s helped for quick summary of current evidence (with referenced journals) and especially quick for looking up new medication side effects. It’s more robust in its LLM for answering nuanced questions than the usual Cochran review/Uptodate that ones used to learning decades ago. A great equalizer for trying to synthesis best practice and when trying to pull quick things from guidelines. And supposed to be able to get CME credit in the future for what one looks up also! Great starting point for being able to jump to a journal reference quickly…
I have been using this platform for over 6 months now, and it is both revolutionary and disruptive. Whether updating medical knowledge or searching for actionable up to date treatment plans, this AI reference is invaluable and beyond game changing. My patients (and myself) benefit from its powerful results on a daily basis. The answers are both thorough and accurate with extensive reference if you are an AI naysayer. Only negative I can synthesize is clinicians could be rendered obsolete with this phenomenal technology. In its current iteration, this tool is an invaluable adjunct to modern day medical practice. Adopt it or be left to perish! Much gratitude and many thanks to all who have made this technology readily available to all medical professionals and at no monetary cost. Truly amazing. Keep up the stellar work!
I find that I have made OpenEvidence a tool I use every single day and multiple times daily at that. For a year I used it often but held it at arms length while sizing up the technology. I found it provided zero factual errors in that time. While in the early days I found a few of the searches/answers to be superficial and of no real help, that changed over time so that in the past year the quality, depth and breadth of answers have been remarkable. I find it provides concise reviews of content I have not recently visited and every day I learn something. I wholeheartedly recommend this tool for busy Internists.
Incredible resource for clinicians. Gone are the days of sifting through endless journal websites/clinical trials trying to find an EBM answer to my clinical questions. Most clinical questions I have in an obscure, uncommon situation where the data is not clearly established, with time constraints it is impossible to sift through endless journal articles to find the answer myself. OE harnesses powerful AI technology to do the data sifting for me instantaneously, and can tell me what the data says on an obscure, clinical query where there is no obvious answer from traditional sources. Linking the journal studies/info is extremely helpful so I can go straight to the source myself if needed.
I’ve experimented with ChatGPT as well for medical guidance and with appropriate wording requests it is often helpful summarize medical guidelines, etc…. BUT I’ve found mistakes at times, so have used with caution. OPEN EVIDENCE however is so much more helpful in pulling together from only medical sources& is easy to see provided sources quickly & follow up with additional questions, rationales, pharmacokinetics, pathophysiology, etc. Love it, especially to help my continued learning/critical thinking as a fairly new practitioner, without extensive time scanning multiple articles/sites.
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The app has been providing me with great and accurate information so far, with really good references and precise data, the only issue is that their servers are really bad, i can only ask around 1-3 questions before they crash and tell me they are having troubles processing my question due to high volume of traffic, this hasn’t happened to me before on any other AI that i have been using so far, i suggest the creators to fix this as soon as possible since their app really works great answering questions accurately but the issue i mentioned is really rendering most of its purposes useless
OpenEvidence is an exceptional clinical tool and a true asset for modern healthcare providers. It delivers clear, concise, and trustworthy evidence at the point of care, allowing rapid synthesis of guidelines and primary literature without compromising quality. The interface is intuitive, and the evidence presentation makes it easy to assess strength, relevance, and clinical applicability in real time. In fast-paced environments, OpenEvidence meaningfully supports evidence-based decision-making and improves confidence in patient care. I would strongly recommend it to any clinician committed to delivering high-quality, data-driven medicine. — Lewis Perna, FNP
This app has been a game changer and has become my go to reference when I encounter something in my practice that I have not delt with before. I still collaborate with my specialist colleagues but now when I do, I generally have a plan I intend to take and just need to verify it with my specialist. I also really like having some specific numbers/statistics presented by this app from real studies to use and reference when presenting a plan of action to a patient. My patients respond well to that kind of specific data.
I’m 80, but lucky to have absolutely loved radiology and medicine, such that after retirement at 65, I continued to practice six 7-day weeks/year until 3 months ago. AI, of could, did not exist. OpenEvidence is phenomenal. It keeps me up to date anytime i want to review a subject or investigate a medical topic which I don’t know much about. I could go on forever about the incredible value of this website. Thanks for creating this, which uses AI to be so incredibly valuable to such a noble and important profession.
This app has been blocked to UK users. We don’t have anything else here that I can see as being even half as good. I used the app daily for CPD, literature review, reviewing interesting case studies, even to help me explain issues to patients. It was the best thing that had ever happened to democratise access to the best quality medical knowledge globally. What can we do to regain access? What are the issues so we can try to help from this end. I’m writing to my MP.
Succinct, accurate, well organized, and fully referenced snapshots of issues… available in seconds. After forty years of effort to find or develop software to subtract some of the drudgery from internal medicine, this is the biggest step toward that goal ever. It will be even more important going forward to ensure that medical research produces well controlled and critically appraised papers to add to the repository. This tool has the potential to disrupt the practice of medicine; the time to enjoy it is now.
This was a seemingly random email that I received, but it’s been an absolute game changer. As a physician, it’s incredibly valuable to be able to run an evidence based search of the literature and not have to sort through the Google quagmire. I’m currently putting together a grand rounds talk. I have an instantaneous answer to my questions with citations that saves me hours of pubmed searches. Machine learning will change the way that we practice and this is a step in that direction.
As a current medical student, this is easily the best, most accurate resource I have used to find an answer for clinical questions. From summarizing studies to explaining the rationale behind management options, OpenEvidence does it all with accurate references. Although I can find a lot of this information elsewhere, the succinct explanations keep me coming back. I will continue to recommend this app to everyone in healthcare as a must-have.
Fantastic app! Provides accurate and very helpful answers for an enormous variety of clinical questions. Incredibly helpful to support my patient management. I didn’t notice any hallucinations so far - this makes Open Evidence much more trustworthy than other apps, including ChatGPT and other competitors. Sources including guidelines are very well selected and the list of used references is fantastic. Really a game changer to improve the daily work flow of a physician like me!
This app came to be a Game changer not only into my practice but as well for aiding and educating my patients . Other apps as UpToDate are valuable but too tedious most of time due to extent of explanations. This app has all I looked for in terms of strength , knowledge , applicability and “right there” concise and solid evidence-based medicine. If you value what you do by passion ,and this should be practicing evidence- based medicine , Open Evidence is a must. OE rocks!
As a new primary care attending, I have found this app to be very helpful with some of the more obscure questions that patients ask, including some references on supplements and other things. It is a nice quick reference to before I walk in the room and has up to date information on current trends. I have definitely been recommending it to friends and colleagues.
This app is probably the best thing I’ve found while practicing medicine. The idea that every answer is pulled from medical journals and other trusted resources is reassuring. It has helped me consider differentials I hadn’t thought about, decrease/increase what I’m ordering, helping me decide if something is an immediate referral vs waiting, and specifies best imaging/next steps! Highly recommend.
This is a truly awesome tool. Responses are complete, accurate, well referenced, appropriate. One of the greatest strengths of this tool is also something that can sometimes be frustrating, but is entirely appropriate: it resists overstating, even if pushed. This distinguishes it from many other AI tools. This is the future, and it is going to improve medical care and save lives.
Pleasantly surprised with the degree of accuracy of this AI-generated resource, which provides actionable medical information tailored to real world patient care, avoiding overemphasis on the theoretical as opposed to the practical. A ready resource companion for board examination review as well! Highly recommended for the busy physician and the inquisitive student alike!
Completely blown away by the precise step wise explanations including pitfalls in measurements. Medicine has changed forever by this amazing application. I had been an interventional cardiologist for 20 years. I believe we should be talking of clinical medicine before OpenEvidence and after in the coming years.
Great app! It’s super easy to use and super educational, and i always get quick, helpful answers. It also gives sources if you wanna dive deeper. it’s honestly become my go-to for medical stuff. highly recommend it to anyone who wants a bit of peace of mind or honestly a bit more info on everyday medical questions.
I’m a curious RN and FNP student. I had been using Grok to learn about conditions and treatments and to explore case studies. I’m so glad I found OE! I call it “The Evidence” in conversation. It feels like a playground and I’ve just gotten started with exploring what it can do. I am so excited to use this tool both during school and in practice.
I use OE every day on my practice to look up medical information, latest best practice guidelines from major publications, write education for patients that far exceeds the education quality provided by the EMR we use. OE will even translate to and from several languages. I am shocked it is free to use.
I have been using this app for quick searches during clinic, and it has proven to be an invaluable resource. The information provided is consistently accurate, with concise and reliable references. It has become an essential tool for my day-to-day practice.
There have been a few times where the answer to my question was not quite on point, but I am finding this tool helpful in my day-to-day practice. Excited to see what the future holds for this platform!
Really beneficial quick search for that searing question honestly. sometimes requires very good specific precising in order to get the desired answer instead of an aberage answer. but if u use it right, its incredible. 10/10
I find open evidence to be extremely fast and very accurate when I have a clinical question. I frequently use it to make sure I am doing everything in the most up-to-date fashion.
I rarely write reviews, but I have to say that this has really been an outstanding addition to my medical library and knowledge. It does not substitute for full text digestion of articles, but it definitely helps with a quick birds-eye view.
This app is so useful. It's also nice that it can't be cluttered up by non-clinicians. The fact you need a health care provider # helps keep the app good and useful. It's very helpful when looking for evidence to support a claim to my patients. It's also great to help if I'm in a rut.
I was introduced to OpenEvidence by a fellow medical colleague. I am absolutely delighted at the information available and thankful for such a valuable tool being free for providers. This OpenEvidence has allowed me to be more accurate and confident during patient encounters.
Open Evidence has become the new UpToDate when it comes to quickly accessing info on rarely used meds. It’s also great for getting verifying that your independent interpretation of labs, imaging, etc. are correct.
This AI is helping me guide my own learning process in residency by giving me fast searching for both the most cited and most recent studies in different practice areas. It’s not infallible at summarizing but it gives me great blurbs to start off with.
I have been testing this rigorously. A few things it has gotten wrong, or rather, not fully correct, but with some fine tuning of the verbiage I was still able to get there.
Don’t think twice. This app is a game changer. Able to now claim CME as well. However, CME is claimed only on website and not app. Hopefully this gets fixed on future updates. Nonetheless, it’s a fantastic app. A must have.
I’ve been using Uptodate for a long time, but this app is on another level. I hope they keep adding more evidence based content, and keep improving it. Excellent so far!
I really love OE and it helps in plenty of clinical scenarios. I especially love being able to read journal articles cited. My one complaint is that there is not a saved articles library feature. I feel it is very cumbersome to try to find specific articles that I had read in some conversation when I am trying to reference it later. Having a library feature would be great. Especially if it had an option to jot down some notes/thoughts about the article too. Thanks!
Very useful for medical research and work — it brings together all the useful primary literature I don’t have time to search through in one place, and answers my questions with evidence from these.
The website, and now this app, are amazing. I’m in love with it! It’s super helpful and I really like how it provides the references for where it gets its info for. As with all things AI, the onus is on the user to fully search and verify the answers.
As a physician, I have tested the application in my speciality field (psychiatry) and have as yet to find it providing inaccurate information or hallucinating. I primarily use it to address questions that are outside of my specialty field.
I’ve been using OE for a few weeks now and it definitely adds tremendous value. Please keep adding to its universe of knowledge and incorporate the next generation of reasoning that Open AI keeps hinting at releasing soon.
OpenEvidence has been a total game changer in my practice! I get quick and thorough answers that are accurate and actionable. It’s been amazingly helpful with letters of medical necessity and appeals. And the best part is that it’s free!
Answers are ACCURATE and even site sources. Great tool to have in your pocket and absolute game changer. Just with there was a platform for my MacBook (app only available on iPad and phone)
Looks like the future of medicine is in front of us. It’s possible that there are other resources that I’m not aware of. But this App took it to a different level. Congratulations to whoever is managing!
If you take care of patients, this resource will make your life easier. There’s no reason not to lean in and spend less time looking for answers in nuanced clinical practice.
Great resource! Very accurate because it sources only the most well respected and up to date data to support its conclusions! Has become my primary medical resource!
I query this app many times per week, on wide ranging topics. In addition to helpful answers to my questions, the references allow for rabbit hole exploration when desired.
I have been using this app a year or more and it is the go-to source for all things medical. I have told many other physicians about it. Thanks folks.
Extremely useful tool in daily practice backed by true medical evidence for professionals. Helps to widen my differential diagnoses and add additional treatment considerations
So useful and informative using current information from medical journals.
What took me 8 hours in the library now takes 30 seconds
Amazing app!
Easy to use. Provides sources with quick links so you can evaluate information post.
I started using OpenEvidence about 1 month ago when I found out about their web version. It has replaced every other medical reference. I use it every day in my work. It gives thorough, accurate, concise and immediate answers to any medical question. Every clinician who I have shown it to has told me that they found it to be practice changing. Amazing work!
OE is one the best AI medical sources that i get the best recommendations for my tough cases.
OpenEvidence Negative Reviews and Ratings
This is a fantastic app. It generates fast, clear and succinct answers to questions, but there are some issues to be aware of. I have found that in practice, you REALLY need to use the right prompts, or some of the information you receive may be incomplete or misleading. For instance, it may not provide you information pertinent to special populations (ie pregnancy), unless you think to ask for this specificity. I also found that when asking about treatment options, it may provide options but will not go into details of the risks associated with these options unless specifically prompted. I also noticed it will sometimes generate information that is not fully correct if the prompt is too general. For instance I typed “magnet runaway pacemaker.” I expected to get information on the runaway pacemaker condition and how to use a magnet to stabilize it. But what I got was “A magnet runaway pacemaker refers to a malfunction of a pacemaker that results in erratic and rapid pacing due to the inappropriate activation of the device’s magnet response mode.” I think this will eventually be an incredible application of AI for as a tool for medical practice. Looking forward to future updates.
It is known that AI provides inaccurate information. This app isn't an exception. This app is actually particularly dangerous due to it being marketed as a tool for health professionals. This app will result in patients being neglected further due to it pulling from outdated and inaccurate medical journals. CBT isn't an adequate treatment for CFS and AI isn't an adequate replacement for looking at medical research yourself. If you're a doctor using this you should be ashamed that you're risking the health and wellbeing of your patients just to make your day a little bit easier. If you don't know about something a patient comes to you for, tell them you don't know. Tell them you'll find someone to help. Don't type it into an app and act like you helped someone.
Probably 90% of the time when I ask this app a question, it gives me a generic error message saying that my question was "outside the scope of OpenEvidence" (because apparently this app can't recognize context like ChatGPT can). If you have a **very** basic question, this app might work for you. But if your question has literally any depth whatsoever, searching on PubMed and reaching your own logical evidence-based conclusions (or just paying for and using ChatGPT) is probably going to be 100 times more helpful than using OpenEvidence. Very mediocre and lackluster from my personal experience.
I was given this website by Cardiology Made Easy program. I was able to set up email and password. However, unable to set up an account. It asks for occupation and mine is listed but it keeps asking for an NPI number. Why is it asking an RN for an NPI? I have no problem proving I’m a nurse and my credentials. I can’t give a true star rating since I can’t even get past enrollment.
Cannot even log in the app



